About Mavedb Link
Mavedb Link is an MCP server in the Healthcare category: mCP server for MaveDB: quantitative variant-effect scores from Multiplexed Assays of Variant Effect (MAVE) and deep mutational scanning — functional evidence as typed tools for LLM agents.
Install
git clone https://github.com/berntpopp/mavedb-linkThis server has no ConduID identity, so agent calls to it are not receipted. Pin the version you install and review the source before granting it credentials.
Tools (15)
find_variantOne variant's score + class across **every** score set — anchored by GA4GH VRS id, `variant_urn`, or a bare `hgvs=` (+ optional `gene_symbol=`) resolved to VRS internally
Parameters not published.
get_classified_variantsEvery variant in a calibrated functional class (e.g. all `abnormal` / PS3), with scores
Parameters not published.
get_collectionCurated collection members (URN from a score set's `official_collections`, or mavedb.org)
Parameters not published.
get_diagnosticsLive API reachability + version + mirror/cache/runtime metrics
Parameters not published.
get_experimentExperiment record + child score-set URNs
Parameters not published.
get_gene_score_setsAll published MAVE datasets for an HGNC gene symbol (lean listing with a `has_calibrations` flag)
Parameters not published.
get_hgvs_validationValidate an HGVS string and surface *why* it is invalid (reference mismatch, missing accession)
Parameters not published.
get_mapped_variantsGenome-mapped GA4GH VRS alleles + ClinGen Allele IDs for a score set
Parameters not published.
get_score_distributionServer-side summary stats (quartiles, histogram) + a query score's percentile and class
Parameters not published.
get_score_setScore-set record (targets, publications, licence) **+ `score_calibrations`: ACMG/OddsPath thresholds**
Parameters not published.
Show all 15 tools
get_server_capabilitiesDiscovery surface: tools, signatures, limits, error taxonomy
Parameters not published.
get_variant_scoreOne variant's score + per-calibration classification (by variant URN, or score-set URN + HGVS)
Parameters not published.
get_variant_scoresThe quantitative variant × score table (paged); each row carries its calibrated functional class
Parameters not published.
search_experimentsFull-text experiment search
Parameters not published.
search_score_setsFull-text + faceted search of score sets (gene, organism, author, journal, keyword)
Parameters not published.
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