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MCP servers tagged bioinformatics

167 live MCP servers tagged "bioinformatics", ranked by trust score. Tags come from package metadata and repository topics, so this list covers servers across every category that work with bioinformatics.

167
live servers
39
avg trust
1.8K
most stars
51

Hpo Link

berntpopp

MCP server for the Human Phenotype Ontology (HPO): phenotype term lookup, the is_a hierarchy, cross-ontology mapping, and gene–phenotype–disease associations from HPO and HPOA.

★ 1updated 14 days ago
34
52

Awesome Bio Agents

kikixiong

A curated collection of AI agents, harnesses, MCP servers, skills, tools and benchmarks for biological research.

★ 1
34
53

Heuris BioMCP

SachinGawande2003

BioMCP - Comprehensive MCP server for bioinformatics and life sciences

★ 1
34
54

SDK Typescript

Palald

🚀 Build efficient applications with the MCP SDK for TypeScript, offering optimized performance, real-time communication, and robust session management.

★ 1updated 5 days ago
34
55

STAMP

anaross34167

Solid Tumor Associative Modeling in Pathology

★ 1updated yesterday
34
56

Helix

coindef

A declarative DSL and compiler for reproducible gene-editing design — with LLM agents and an MCP server so any AI agent can drive it safely.

★ 1updated 5 days ago
34
57

Vcf MCP

NahButch

MCP Connector for VCF Genetic Data File(s). Single, multiple, comparison, data setting, etc.

★ 1updated 4 months ago
34
58

Awesome Scientific AI Tools

sparzinhogames-hash

Discover AI tools, MCP servers, and agent skills for scientific research across literature, data, writing, and lab work

★ 1updated 4 days ago
34
59

Lifesciences Research

AI Agent wrappers for Life Sciences APIs (Open Targets, ChEMBL, UniProt). Accelerating drug discovery with Model Context Protocol (MCP) and FastMCP.

34
60

PDBe MCP Servers

PDBe MCP Servers integrate Protein Data Bank Europe resources with LLMs via Model Context Protocol. Provides seamless access to protein structure data through API tools and graph…

34
61

Posebusters MCP Server

Unofficial MCP server for PoseBusters – validate molecular poses via HTTP or Spaces using the Model Context Protocol (MCP).

34
62

Biothings Typed Client

Client that provides typed definitions to biothings client

34
63

SEOSiri-Official/biorobotics

code coordinates using the Model Context Protocol. 🐍 🏠 🍎 🪟 🐧

34
64

GrEBI

HPC aggregation pipeline and API/MCP server for LLM-mediated biomedical data integration

34
65

Nf Runinsights

Nextflow plugin for cross-run benchmarking. Records per-process metrics for every run into a local or shared history store, compares runs against their own history, and flags regr…

34
66

LibreGene

An open-source, agent-ready plasmid editor.

34
67

Stringdb Link

MCP server for STRING v12: protein–protein association networks, interaction partners, and functional enrichment analysis — as typed tools for LLM agents.

34
68

Fgbio MCP Servers

MCP Wrappers for fgbio Tools

34
69

Mgi Link

MCP server for MGI (Mouse Genome Informatics): mouse gene, allele, mutation and phenotype data — the MGI marker page as structured tools, served from a local SQLite index.

34
70

Oncotarget Luad

Scientific MVP for LUAD target prioritization using knowledge graphs, GraphSAGE, and GraphRAG.

34
71

Mygene MCP

MCP server for MyGene.info API

34
72

Mydisease MCP

MCP server for MyDisease.info API

34
73

Gtex Link

MCP server for the GTEx Portal: tissue-specific gene expression — median and per-sample TPM, top expressed genes per tissue, and gene/transcript annotation — as typed tools for LL…

34
74

Genereviews Link

MCP server for GeneReviews: the expert-authored, peer-reviewed gene–disease chapters on NCBI Bookshelf, served as a searchable corpus of individually citable passages.

34
75

Autopvs1 Link

MCP server for AutoPVS1: automated ACMG PVS1 loss-of-function evidence for sequence variants and copy-number variants — variant interpretation as typed tools for LLM agents.

34
76

Biomedical Terminology Service

The BioMedical Terminology Service (BTS) is a self-hosted platform that provides one API for searching, traversing, mapping and semantically comparing concepts across major biomed…

34
77

Litvar Link

MCP server for NCBI LitVar2: search the biomedical literature by genetic variant — the index linking variants to the publications that mention them, as typed tools for LLM agents.

34
78

Pubtator Link

MCP server for NCBI PubTator3: biomedical literature search with gene, variant, disease and chemical entity annotation — returns compact, citable passages instead of raw BioC.

34
79

Gnomad Link

MCP server for gnomAD (Genome Aggregation Database): variant allele frequencies, gene constraint, coverage, structural and mitochondrial variants, and liftover — as typed tools fo…

34
80

Mavedb Link

MCP server for MaveDB: quantitative variant-effect scores from Multiplexed Assays of Variant Effect (MAVE) and deep mutational scanning — functional evidence as typed tools for LL…

34
81

Mondo Link

MCP server for the Mondo Disease Ontology: disease term lookup, the is_a hierarchy, and cross-ontology mapping across OMIM, Orphanet, DOID, NCIT, UMLS and MeSH.

34
82

Genepattern MCP

MCP server that lets AI assistants (Claude, Cursor, Copilot) run GenePattern bioinformatics modules, manage cloud jobs, and access genomic data — all through natural language.

34
83

Mutcompute MCP

MutCompute MCP server for protein mutation effect prediction

34
84

Boltzgen MCP

BoltzGen MCP server for protein binder design

34
85

Bindcraft MCP

BindCraft MCP server for de novo protein binder design

34
86

Boltz MCP

Boltz2 MCP server for protein structure and affinity prediction

34
87

Claude Code Biology Research

?? A comprehensive guide to using Claude Code as an AI-powered assistant for computational biology, bioinformatics, and biomedical research

34
88

Agentic Genomics

Connect whole-genome sequencing data to AI coding assistants via the Model Context Protocol (MCP). Setup guides for GeneChat-MCP, OpenCRAVAT-MCP, and Pomera across Antigravity, Co…

34
89

Netmhc2pan MCP

NetMHCIIpan MCP server for MHC Class II binding prediction

34
90

Prottrans MCP

ProtTrans MCP server for protein embeddings and fitness modeling

34
91

Alphafold3 MCP

AlphaFold3 MCP server for protein structure prediction, supporting batch prediction

34
92

Genefoundry

A modular registry for trustworthy, evidence-based genomic analysis powered by Model Context Protocols (MCPs). Bridging AI and clinical genomics with traceable, validated data ret…

34
93

Proteinmpnn MCP

ProteinMPNN MCP server for protein sequence design (inverse folding)

34
94

Ev Onehot MCP

EV+Onehot MCP server for protein fitness prediction combining evolutionary coupling and one-hot encoding

34
95

Rfdiffusion2 MCP

RFdiffusion2 MCP server for protein structure generation (backbone)

34
96

Oncora

Oncora — A Reproducible, Uncertainty-Aware Agentic Reasoning Platform for Oncology Drug Discovery (Rust-native, on-prem, MCP)

34
97

Flowproof MCP

Run reproducible bioinformatics pipelines from an AI assistant over MCP, with verifiable provenance

34
98

Chilecule

Agentic drug discovery workflows on fully open-source tooling: RDKit, AutoDock Vina/smina, fpocket, ChEMBL. MCP tool servers + Claude agents, with a retrospective validation harne…

34
99

Litmuz Agent

Claim-level verification for life-sciences research agents: honest, auditable, per-claim traffic-light verdicts against the primary literature and genomic reference data. MCP-nati…

34
100

Mychem MCP

MCP server for MyChem.info API

34
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